NS Bio
BACT-OUTBREAK-04 · COMPLETE
CARBAPENEMASE · DETECTED
STORAGE · UK · ENCRYPTED
16S · DIVERSITY · 0.84
Sovereign UK microbial bioinformatics

Pathogen genomics and microbial analysis, built to specification.

NS Bio designs custom analysis pipelines, processes sequencing data, and trains scientists for healthcare, public-sector, and academic-research clients. All work is performed on sovereign UK infrastructure — your data never leaves these shores.

Sectors
Healthcare · Public sector · Research
Sovereignty
UK only · No cloud egress
Compliance
ICO · Cyber Essentials
Infrastructure
Self-hosted · Encrypted
About

A small consultancy, doing the work properly.

Founded in 2023, NS Bio operates as a deliberately small, technically-led practice. Every project is delivered personally rather than handed down a chain of associates.

We work exclusively with anonymised samples on infrastructure that is self-hosted, segmented, and audited within the United Kingdom — engineered for the regulated environments that healthcare bodies, government agencies, and research institutions operate in.

For larger pieces of work we can scale up via a network of trusted contractor bioinformaticians, drawn from UK academic and public-sector backgrounds.

Sovereignty & Trust

A bioinformatics partner you can defend in any audit.

Sovereign UK capability is no longer a nice-to-have. Increasingly, healthcare and public-sector clients need to demonstrate that pathogen, sequencing, and patient-adjacent data has not crossed jurisdictions. NS Bio is engineered for that requirement from the ground up.

UK sovereign

All data and processing remain inside the United Kingdom. No cross-border transfers, no foreign cloud dependencies, no data egress.

Self-hosted

Owned infrastructure end to end. No AWS, Azure, or Google. We control the entire stack — hardware, network, application.

Encrypted at rest

AES-256 encryption on storage, TLS in transit. Encryption keys are held only by NS Bio and never escrowed to third parties.

Full audit trail

Every transfer, processing step, and access is logged. Documented chain of custody, ready for assessor or auditor handover.

Services

Three areas of practice, delivered end to end.

Each engagement is scoped to your data, infrastructure, and team — not delivered from a fixed catalogue.

Bioinformatics consultancy & pipeline development

Design and implementation of analysis pipelines tailored to your sequencing platform, organism, and operating environment. From single-tool integrations through to full Nextflow or Snakemake workflows.

Nextflow Snakemake Docker HPC / Cloud

Pathogen genomics & data processing

End-to-end processing of microbial sequencing data — quality control, assembly, speciation, AMR profiling, phylogenetics, and outbreak analysis. Performed with full chain of custody.

Illumina Nanopore Bacteria Metagenomics

Training & education

Tailored training in microbial bioinformatics for laboratory and research teams. Sessions are scoped to existing tooling and skill levels, with hands-on materials you keep afterwards.

NGS Phylogenetics Biopython Long-read
Featured pipelines

Production-ready analysis for microbial sequencing.

Three flagship pipelines covering the work we do most often. Each can be run on your data with a documented, reviewable report at the end.

Bacterial analysis

Whole-genome analysis · isolates

Quality control, assembly, speciation, antimicrobial resistance profiling, MLST typing, virulence gene detection, and phylogenetic placement — from raw reads to annotated report.

Illumina Nanopore Hybrid assembly AMR MLST Phylogeny
View example report Soon

16S / ITS analysis

Microbiome composition · diversity

Amplicon sequence processing, ASV inference, taxonomic classification, alpha and beta diversity metrics, and differential abundance testing — for both bacterial (16S) and fungal (ITS) communities.

16S ITS DADA2 QIIME2 Diversity Taxonomy
View example report Soon

Primer analysis

Design · validation · specificity

In-silico PCR, primer specificity testing against reference databases, coverage analysis across target taxa, and design recommendations — for diagnostic, surveillance, and research primers.

In-silico PCR Coverage Specificity Design Validation
View example report Soon
Process

A clear path from first conversation to delivered results.

Most projects move through four stages. Timelines vary by scope; expect a written quote within a week of the first call.

Step 01

Discuss

A short scoping call to understand your data, question, and constraints.

Step 02

Quote

A written proposal within a week, with clear deliverables and timing.

Step 03

Process

Secure data transfer, analysis on encrypted infrastructure, regular updates.

Step 04

Deliver

Reports, raw outputs, and a documented handover. Iteration if needed.

Coming soon

A secure client portal for uploads, quotes, and results.

Active clients will soon access a dedicated portal for transferring sequencing data, requesting quotes, and downloading completed deliverables — all under their own multi-factor-protected login, with a complete audit trail. Built on self-hosted, encrypted UK infrastructure.

portal.ns-bio.co.uk
BACT-OUTBREAK-04Results ready
16S-ENV-2026-Q2Processing
METAGEN-PILOTQuote sent
AMR-SURV-12Closed

Have a sequencing
problem you'd like to talk through?

Initial conversations are free and confidential. Most projects begin with a short scoping call — followed by a written quote within a week.